ire1α kinase-in-1 — TargetMol Chemicals

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Search Results for " ire1α kinase-in-1 "

Compounds

Cat No.	Product Name	Targets
T9564	IRE1α kinase-IN-1	IRE1
	IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph...	IRE1
T63511	IRE1α kinase-IN-4
	IRE1α kinase-IN-4 (compound 6) is a potent inhibitor of IRE1α, exhibiting a Ki value of 140 nM. It acts as an ATP-competitive ligand for IRE1α [1].
T79062	IRE1α kinase-IN-8	IRE1
	IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, serves as a potent inhibitor of IRE-1α. This compound is utilized in research pertaining to diseases linked to the unfolded protein response and regulated I...	IRE1
T79063	IRE1α kinase-IN-9	IRE1
	IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM. It is suitable for research into diseases linked to the unfolded protein response or regulated IRE1...	IRE1